Clinical and economic burden of postoperative nausea and vomiting: Analysis of existing cost data

Best Pract Res Clin Anaesthesiol. 2020 Dec;34(4):681-686. doi: 10.1016/j.bpa.2020.07.003. Epub 2020 Jul 18.

Abstract

Postoperative nausea and vomiting (PONV) is an undesirable outcome that occurs in up to 30% of patients. Over the years, the cost of treating PONV has decreased due to the availability of cheaper yet effective antiemetics. Limiting PONV development benefits the hospital system as studies have shown that prevention is associated with shorter post-anesthesia care unit (PACU) stays as well as decreased supply costs and staffing burden. The financial burden for prophylaxis against PONV has been shown to be less than what patients are willing to pay to prevent the development of PONV. Studies have also shown that prevention of initial development of PONV limits readmission rates, which is beneficial to both the patient and the hospital. Owing to recent economic analysis and reductions in antiemetic prices, the patient's preference for comfort, the hospital's commitment to providing the best care, and the system's desire for fiscal prudence are aligned. This culminates in recommending PONV prophylaxis for all patients undergoing anesthesia.

Keywords: PONV; costs; economics; nausea; outcomes; vomiting.

Publication types

  • Review

MeSH terms

  • Anesthesia / adverse effects
  • Anesthesia / economics
  • Antiemetics / economics
  • Antiemetics / therapeutic use*
  • Cost of Illness*
  • Data Analysis*
  • Humans
  • Postoperative Care / methods*
  • Postoperative Care / trends
  • Postoperative Nausea and Vomiting / chemically induced
  • Postoperative Nausea and Vomiting / economics
  • Postoperative Nausea and Vomiting / prevention & control*
  • Pre-Exposure Prophylaxis / economics
  • Pre-Exposure Prophylaxis / methods*
  • Pre-Exposure Prophylaxis / trends

Substances

  • Antiemetics